Hailed by Strad magazine as a "strong artistic personality", Singaporean violinist, Kam Ning has gone on to perform all over the globe both as soloist and chamber musician. She was the Second Prizewinner at the Queen Elisabeth Competition in 2001 and was praised by Belgium's De Standaard as "manifestly the best violinist of the competition". She also won the Flemish Radio and Television Audience Prize in that year. She has performed under the batons of conductors such as Yehudi Menuhin, Lorin Maazel, Okku Kamu, Lan Shui, Louis Langree and Steven Smith with orchestras such as the Cleveland Orchestra, National Orchestra of Belgium, Liege Philharmonic, Singapore Symphony, Orchestra Svizzera Italiana, Malaysian Philharmonic and City of London Sinfonia. Kam has also collaborated in chamber music with musicians such as Yehudi Menuhin, Patricia Kopachinskaja, Marie Hallynck, Qin Li-Wei and Francis Kam amongst many others. 

Kam released her first recording in 1997, featuring the works of Enesco, Sarasate, her father, Kam Kee Yong. Since then she has released "Transatlantic", dedicated to the music of the Americas,  "Cicada", dedicated solely to the music of Kam Kee Yong and her recording of August De Boeck's Violin Concerto with the Flemish Radio Orchestra conducted by Marc Soustrot, under the Etcetera label. American Record Guide has praised "Transatlantic" as "energetic and virtuosic" as well as having "humour, lightness and strength". has called Kam's playing "stunning" and "fiendish" and a 10/10 was given by the Belgian music magazine "Crescendo" for this original recording. Her disc,"Road Movies" was released in 2013 on Meridian Records, UK. Featuring the music of John Adams and John Corigliano, this disc partners Kam with pianist, Albert Tiu and has earned rave reviews from Fanfare magazine. Her latest release on Etcetera Records of works by Stravinsky, Mendelssohn and Prokofiev with Belgian pianist and Queen Elisabeth Competition winner, Liebrecht Vanbeckevoort, has also won praise from Klara Radio and Opus Klassiek.

In October 2002, Kam was invited to perform at the National Inauguration of the Esplanade Theatres on the Bay Concert Hall in Singapore, where she partnered Sarah Chang in Bach's double violin concerto with the Singapore Symphony Orchestra, conducted by Lan Shui. She has also been honoured by the National Arts Council of Singapore with the Young Artist Award, presented in 2000 to a young artist of extraordinary talent. She has been featured on the documentary "Portrait of the Artist" on SBC, Singapore, and has broadcasted on Singapore's Symphony 92.4FM, BBC Radio 3, Klara and Musique Trois in Belgium and CBC Radio Canada's "Music Around Us" Series at the Glenn Gould Studio. In 2009, Ning was invited to perform at the Singapore President's Command Performance at the Esplanade, a concert at the behest of former President Nathan of Singapore to honour and celebrate Singaporean artists. 

Her interests include unusual repertoire which have brought her into collaboration with artists such as her brother and percussionist, Francis Kam. As a visionary artist with a reputation for musical integrity and imagination, Kam also has a particular love for contemporary music. Between 2011 and 2017, she was the Artistic Director of Het Kamerorkest Brugge, a conductorless chamber orchestra with a focus on 20th and 21st century music. Under her leadership and adventurous programming, the HKOB gained a reputation as an orchestra with an exciting energy for a new generation in classical music.  She has also been invited to guest lead and direct the strings of the Rheinische Philharmonie Koblenz in seasons 15/16, 16/17 and will return there in season 2017/18. Kam has also directed the Re:Sound Collective in Singapore in season 16/17. As an artist who loves to venture off the beaten path of classical musicians, Kam is also a founding member of Loco Motive, a bluegrass, jazz and funk trio with cellist, Sebastien Walnier and bassist, Lisa De Boos. 

Since September 2017, Kam has joined the faculty of the Conservatoire Royal de Bruxelles as Professor of Violin. 

As a born-again Christian, she has been an Ambassador for International China Concern, a Christian charity that cares for the abandoned and disabled in China. 

Kam plays on a 1658 Nicolas Amati on generous loan from the Rin Collection, Singapore.